The book covers the state-of-the-art research knowledge and results on the innovative theories, methodology and applications of artificial intelligence and its sub-domain like deep learning in different areas such as medicine, economy, education, law, smart city, government, industry etc. Moreover, the book aims to provide a platform for researchers and practitioners for both academia and industry to share the information about cutting-edge developments in the field of artificial intelligence. The chapters in this book integrated approach toward global exchange of information on technological advances, scientific innovations and the effectiveness of various regulatory programs toward AI application in medicine, biology, chemistry, financial, games, law and engineering. Real examples from academia and industry give beyond state of the art for application of AI in different areas. These chapters are extended papers from the Third Serbian International Conference on Applied Artificial Intelligence (SICAAI), which was held in Kragujevac, Serbia, on May 23–24, 2024.