This book offers a unique perspective on the preparation, characterization, and diverse applications of polylactic acid (PLA) blends in tissue engineering, drug delivery, and medical textiles. The chapters explore critical areas such as the fabrication of PLA-based biomedical foams, the controlled release of drugs from nanocomposites, and the development of antifouling membranes through electrospinning. The authors provide analysis on the properties and sustainable applications of PLA, offering readers a comprehensive understanding of its potential to transform medical and environmental technologies. Readers will discover detailed discussions on the preparation and characterization of PLA blends, as well as their use in innovative applications like 3D printing and the creation of biocidal particle membranes. The book also addresses key questions about the challenges and opportunities in the field, inviting readers to consider the future directions of PLA research and its impact on sustainable development. This volume is an essential resource for researchers, professionals, and students in biotechnology, biomedical engineering, and related fields. It offers valuable insights into the latest advancements and challenges in the use of biodegradable polymers, making it a crucial reference for those seeking to expand their knowledge and contribute to the development of sustainable medical solutions.