This book constitutes the proceedings of the 26th International Conference on Business Information Systems, BIS 2026, which took place in Prague, Czech Republic, during June 10-12, 2026. This year's theme was "From Hype to Impact: Turning AI into Real Business Value". The 25 full papers and 6 short papers included in the proceedings were carefully reviewed and selected from 73 submissions. They were organized in topical sections as follows: Strategy, Architectures and Information Maturity; Information Safety; Trustworthy AI; Process Management and Automation; AI for Product Development; From Text to Knowledge; Speech Recognition; Innovations in Machine Learning; Requirements for AI and BI Systems; and Various Applications.