The “Cancer Metastasis, Management and Complications: An Interdisciplinary Approach” is the twentieth volume of the “Interdisciplinary Cancer Research” series, publishes an overview of cancer metastasis, management and complications. The volume starts with a chapter on musculoskeletal malignancies, followed by chapters on mechanisms of tumor growth and metastasis and transmigration of cancer Cells across the endothelium. After discussion on treatment of the oligometastatic patient, epidemiology, diagnosis, management, and prognosis of spinal metastasis are discussed. The effects of angiotensin-converting enzyme inhibitors on metastasis-associated myeloid cells, as well as multidisciplinary management of colorectal liver metastases are oral cavity are explained in subsequent chapters. Physical activity, physiotherapy, rehabilitation, and palliative care in cancer patients are fully discussed in other chapters. The other chapters focus on cancer complications. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for those who wish to have an update on cancer metastasis, management, and complications.