This book provides a general overview and original analysis of new developments and applications in several areas of Computational Intelligence and Information Systems. Computational Intelligence has become an important tool for engineers to develop and analyze novel techniques to solve problems in basic sciences such as physics, chemistry, biology, engineering, environment and social sciences.  The material contained in this book addresses the foundations and applications of Artificial Intelligence and Decision Support Systems, Complex and Biological Inspired Systems, Simulation and Evolution of Real and Artificial Life Forms, Intelligent Models and Control Systems, Knowledge and Learning Technologies, Web Semantics and Ontologies, Intelligent Tutoring Systems, Intelligent Power Systems, Self-Organized and Distributed Systems, Intelligent Manufacturing Systems and Affective Computing. The contributions have all been written by international experts, who provide current views on the topics discussed and present recent, original insights from their own experience in these fields.