Providing a comparison between context in Europe and the US, this volume investigates the digital transformation of health systems, comparing strategies for digital development while identifying both key innovations and future challenges. The book covers a wide spectrum of topics, from explaining the nature of individual innovations to an analysis of demand-side and supply-side barriers, including funding issues and technological access. It also explores where digitalization is already playing an important role, for example, in clinical trials and disease modeling. Concluding with guidance for policy recommendations, this important book will interest students, scholars, and practitioners across health and social care, medicine, and beyond. The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons [Attribution-Non Commercial-No Derivatives (CC BY-NC-ND)] 4.0 license.