This book presents a timely and comprehensive overview of how cutting-edge technologies are transforming rehabilitation practices for individuals with physical disabilities. Bridging clinical expertise with technological innovation, this volume explores the integration of robotics, virtual and augmented reality, artificial intelligence, brain-computer interfaces, wearable sensors, and telerehabilitation platforms across diverse conditions and populations. Structured around seven thematic chapters, the book addresses condition-specific interventions for neurological, musculoskeletal, pediatric, geriatric, and women’s health-related disabilities. It offers evidence-based insights into how technology enhances functional recovery, patient engagement, and healthcare system efficiency. The final chapter critically examines implementation challenges and future directions, emphasizing inclusivity, accessibility, and sustainability. Written by experienced rehabilitation professionals and researchers, this book serves as a valuable resource for clinicians, physical therapists, biomedical engineers, graduate students, and policy makers. It contributes to the growing body of literature at the intersection of rehabilitation sciences and digital health, offering practical guidance for integrating emerging technologies into clinical practice. This book addresses a global need for accessible, technology-enabled rehabilitation and supports the advancement of inclusive healthcare, aligning with the United Nations Sustainable Development Goals (SDGs).