This book contains the refereed proceedings of the 17th International Conference on Business Process Modeling, Development and Support, BPMDS 2016, and the 21st International Conference on Exploring Modeling Methods for Systems Analysis and Design, EMMSAD 2016, held together with the 28th International Conference on Advanced Information Systems Engineering (CAiSE 2016) in Ljubljana, Slovenia, in June 2016. The focus theme for BPMDS 2016 papers was ”Business Processes in a Connected World”, for which three subthemes were identified: business processes for connecting people, connecting intelligent objects to business processes and connecting information/data/knowledge to business processes. The 17 full and 1 short paper accepted for BPMDS were selected from 48 submissions and are grouped into topical sections on process execution support; improving usability of process models; social and human perspectives; new directions in process modeling; consistency, correctness and compliance; process and data mining; and process variability. The intention of EMMSAD is to solicit papers related to the field of information systems analysis and design including numerous information modeling methods and notations that are typically evolving. These ongoing changes significantly impact the way information systems, enterprises, and business processes are being analyzed and designed in practice. The 12 full papers accepted for EMMSAD were chosen from 19 submissions and are grouped into topical sections on fundamental issues in modeling; requirements and regulations; enterprise and software ecosystem modeling; information and process model quality; meta-modeling and domain specific modeling and model composition; and modeling of architecture and design.