This book offers a comprehensive and insightful exploration of biomarker discovery and electro-chemical signaling pathways in brain and cardio-oncology. The integration of these two fields—focusing on organs where electro-chemical signaling plays a crucial yet distinct role—sets this work apart from existing literature. The brain’s complex chemical signaling and the heart’s electrical communication pathways are examined side by side, providing readers with a unique perspective that may yield new insights into the general field of electro-chemical biomarker discovery. Volume 1 of the book lays a solid foundation by thoroughly covering the fundamentals of oncology and biomarker science. Volume 2 builds on this by offering essential foundational information on biomarker discovery, particularly in oncology.