Cross-border regions are newly emerging social spaces stretching across national borders. Globalization makes national borders more permeable and leads to a rearrangement of economic and political interactions. This is particularly pronounced within supra-regional blocs featuring specific internal border regimes. The ensuing opportunities are increasingly seized to create border-spanning discourses and institutions. This is illustrated in the book by a range of experts analyzing cross-border regions in Europe, America, East Asia and Africa.