This book constitutes the refereed proceedings of the 37th IFIP TC 11 International Conference on Information Security and Privacy Protection, SEC 2022, held in Copenhagen, Denmark, in June 2022. The 29 full papers presented were carefully reviewed and selected from 127 submissions. The papers present novel research on theoretical and practical aspects of security and privacy protection in information processing systems. They are organized in topical sections on privacy models and preferences; network security and IDS; network security and privacy; forensics; trust and PETs; crypto-based solutions; usable security; blockchain; mobile security and privacy; PETs and crypto; and vulnerabilities.