This volume brings together peer-reviewed contributions from the International Forum on Knowledge Asset Dynamics (IFKAD), an annual conference dedicated to advancing understanding of the strategic role of knowledge assets in driving sustainable value creation. The selected chapters examine emerging trends, models, and technologies shaping how knowledge is generated, managed, and leveraged across sectors. Organized around thematic areas defined by each edition’s focus, the proceedings offer actionable insights for building innovative, resilient, and human-centered organizations. This work is intended for scholars, professionals, and decision-makers engaged in knowledge management, innovation, and organizational development. For the 20th IFKAD 2025  - the volume presents cutting-edge insights into how artificial intelligence, digital technologies, and emerging business paradigms are transforming knowledge creation, management, and value generation in organizations. Featuring a curated selection of peer-reviewed papers from the 20th International Forum on Knowledge Asset Dynamics (IFKAD 2025), the book spans a wide thematic spectrum—from AI in healthcare and supply chains to digital transformation, sustainable business models, and organizational innovation. It offers actionable knowledge and theoretical advancements that support the design of resilient, future-oriented organizations. The proceedings are intended for scholars, industry professionals, and policymakers engaged in innovation, knowledge strategy, and digital transformation.