This book constitutes the refereed proceedings of the 12th IFIP TC 12 International Conference on Intelligent Information Processing, IIP 2022, held in Qingdao, China, in July 2022.  The 37 full papers and 6 short papers presented were carefully reviewed and selected from 57 submissions. They are organized in topical sections on Machine Learning, Data Mining, Multiagent Systems, Social Computing, Blockchain Technology, Game Theory and Emotion, Pattern Recognition, Image Processing and Applications.