Isotope geochronology is an important tool to help solve geological problems, from volcanology to climatology, from petrology to tectonics and sedimentology. It is difficult to find cutting-edge geological research that does entirely without the information on the timing and the rates of geological processes. This textbook aims to communicate to readers a first-hand experience of the long-and-winding road from sample collection to the publishable presentation and interpretation of results in their entire context. The intended readership includes both undergraduate and graduate students as well as practitioners of other geological disciplines to gain in-depth hands-on experience of isotope geochronology.