This book constitutes the proceedings of the 22nd International Symposium, KSS 2023, held in Guangzhou, China, during December 2–3, 2023. The 20 full papers included in this volume were carefully reviewed and selected from 56 submissions. The volume is divided in topical sections that cover the following topics: data mining and machine learning, complex systems modeling, decision analysis and knowledge management, opinion mining and knowledge technologies.