We stand at the threshold of a transformative era where the convergence of Lean methodologies and artificial intelligence (AI) is redefining operational excellence. This book is a pioneering exploration of this integration, offering a roadmap for organizations seeking to harness AI’s potential while preserving the human-centric values at the heart of Lean. It provides a deep dive into how Lean principles – focused on efficiency, waste reduction, and continuous improvement – can be enhanced through AI-driven intelligence, agility, and innovation. More than just a technical guide, this book is an invitation to rethink the future of work, leadership and culture in an AI-powered world. Lean-AI: A Humanistic Integration of Lean and AI empowers readers with the tools and insights necessary to navigate the evolving landscape of Industry 5.0+. Through real-world case studies, practical strategies, and in-depth discussions, this book illustrates how organizations can leverage AI to accelerate Lean transformation, enhance human performance, and drive sustainable growth. Readers will gain actionable knowledge on integrating AI with Lean tools such as 5S, poka-yoke, single minute exchange of dies, total productive maintenance, and value stream mapping, among others. The book also highlights the critical role of leadership and culture in ensuring AI-driven Lean implementations uplift rather than replace human capabilities. This book is designed for forward-thinking innovators, business leaders, Lean practitioners, and AI enthusiasts eager to explore the synergy between technology and human-centric process improvement. Whether you are an executive driving digital transformation, a Lean expert looking to modernize methodologies, or a professional seeking to understand AI’s role in operational excellence, this book provides a strategic guide to mastering Lean-AI integration. It is an essential read for those ready to challenge conventional paradigms and embrace the future of efficiency, collaboration and intelligent innovation.