This book involves a collection of selected papers presented at International Conference on Machine Learning and Autonomous Systems (ICMLAS 2021), held in Tamil Nadu, India, during 24-25 September 2021. It includes novel and innovative work from experts, practitioners, scientists and decision-makers from academia and industry. It covers selected papers in the area of emerging modern mobile robotic systems and intelligent information systems and autonomous systems in agriculture, health care, education, military and industries.