This book gives the practical introduction for medical physics students and clinical physicists to learn MATLAB programming. The first part of the book explains the MATLAB software layout and ways to get help followed by the demonstration of the fundamentals of MATLAB programming through over 100 examples. The second part of the book features eighteen real-life clinical scenarios and projects and twenty-three scenario expansions. The scenarios cover many of the common clinical medical physics areas including DICOM file manipulation, film dosimetry, brachytherapy application, linear accelerator and CT quality assurance and their automations, medical image processing and analysis. All scenarios include the step-by-step solution as a guidance for readers to learn MATLAB by practicing. The data files (e.g. DICOM) used for all clinical scenarios are provided