Introduction.- Cloud Service Offer Selection.- The MODAClouds Model-Driven Development.- QoS Assessment and SLA Management.- Monitoring in a Multi-Cloud Environment.- Load Balancing for Multi-Cloud.- Fault-tolerant Off-line Data Migration: The Hegira4Clouds Approach. -Deployment of Cloud Supporting Services.- Models@Runtime for Continuous Design and Deployment.- Cloud Patterns.- Modelio Project Management Server Constellation.- BPM in the Cloud: The BOC Case.- Healthcare Application.- Operation Control Interfaces.- Conclusion and Future Research.