This textbook discusses the realm of nanomaterials science, offering a detailed and comprehensive exploration of materials at the nanoscale level. The book breaks traditional boundaries to provide a dynamic investigation of the rapidly evolving field of nanomaterials science. It offers a thorough examination of the subject, encompassing essential aspects such as the properties of nanomaterials, various synthesis methods, characterization techniques, and their diverse applications across multiple disciplines. Nanomaterials for Smart Manufacturing: Fundamental Principles, Theory, Case Studies, and Advanced Applications explores the practical aspects of nanomaterial fabrication, moving beyond theoretical concepts. This textbook is divided into four parts, covering fundamental concepts to advanced applications and case studies, and discusses a wide array of techniques including traditional bottom-up methods like chemical vapor deposition to cutting-edge top-down approaches such as lithography, offering students valuable insights into the precise fabrication of nanomaterials. It covers topics ranging from strength and toughness at the nanoscale to thermal conductivity and nanoscale heat transfer, providing a comprehensive understanding of how these materials perform under various conditions. Additionally, the textbook showcases the tangible impact of nanomaterials across industries such as electronics, medicine, energy, and catalysis. Real-world case studies, examples, and reader comprehension questions illustrate the revolutionary role of nanomaterials in shaping our world. This definitive guide is tailored for students, researchers, and industry professionals seeking to unravel the mysteries of the nanoworld. Serving as a bridge between the macro and micro worlds, this textbook offers a holistic understanding of nanomaterials. Figure slides are available to instructors for qualified textbook adoption.