This volume presents a collection of original and peer-reviewed articles related with the applications of Statistical Physics dedicated to Professor Dr Leopoldo Garcia-Colin, in commemoration of his 80th birthday in 2010. Professor Garcia-Colin has worked in many different fields of statistical physics, and has applied it to biological physics, solid state physics, relativity and cosmology. These are pioneering works of Prof Garcia-Colin involved in all various fields which have their roots in Mexico. His influence is found in each of these works that cover a wide range of topics including thermodynamics, statistical mechanics and kinetic theory applied to biological systems, cosmology and condensed matter, among others.Papers contributed by important experts in the field, such as J Lebowitz, as well as the latest classical applications of statistical physics can be found in this volume.