This book is a comprehensive compilation of current knowledge on the integrated approaches and strategies of sustainable crop improvement. It encompasses a broad spectrum of subjects including the latest developments and understandings of diverse stress management techniques for sustainable crop enhancement, accelerated breeding, and genome editing. It also delves into the development of next-generation crop varieties through genomic selection to ensure food and nutritional security. It showcases biofortification as a solution to combat hidden hunger by increasing the iron, zinc, and vitamin content in staple crops and millets as resilient and nutritious crops, a key player in future food systems. Innovations in grafting and the enhancement of nutritional quality in vegetable crops are explored, along with novel technologies like plasma treatments and bioengineering to improve food and non-food crops. This book deliberates on the digital tools like high throughput phenotyping, bioinformatics, and machine learning, integrated with classical breeding to enhance crop nutrition, resilience, and sustainability for future food and nutritional security. Key features– Enhances researchers' cognitive framework concerning state-of-the-art technologies for cereals enhancement, thereby facilitating the advancement of scientific knowledge in this domain. – Reviews post-harvest and value addition as well as nutrition and human health. – Facilitates a comprehensive understanding of the intricate information network underlying fundamental traits in cereals, thereby enabling researchers to unravel the underlying mechanisms governing key traits. – Accentuates on the utilization of diverse omics methodologies and the implementation of potential cutting-edge techniques to enhance the understanding of cereal genetics and breeding, thus contributing to the expansion of knowledge in this field. – Provides insights into the challenges and possibilities associated with integrating multiomics data, developing models, and deepening our understanding of the biological aspects of pivotal traits in cereals. – Showcases recent breakthroughs in integrative and systems biology techniques, while illuminating prospects in this field, thus paving the way for further advancements in the study of cereals.