This book constitutes the proceedings of the 14th International Conference on Perspectives in Business Informatics Research, BIR 2015, held in Tartu, Estonia, in August 2015. Overall, 49 submissions from 16 countries were rigorously reviewed by 47 members of the Program Committee representing 23 countries. The selected 16 full papers and 4 short papers are included in this volume. The conference theme was "making business information systems interoperable and adaptive in highly interconnected and changing contexts". The papers have been organized in topical sections on business information systems interoperability, business information system requirements and architecture, business process and decision management, business information systems development, and research in progress.