This book reports on the latest developments in computational fluid dynamics and turbulence modeling, with a special emphasis on hybrid RANS-LES methods and their industrial applications. It gathers the proceedings of the Sixth Symposium on Hybrid RANS-LES Methods, held on September 26-28 in Strasbourg, France. The different chapters covers a wealth of topics such as flow control, aero-acoustics, aero-elasticity and CFD-based multidisciplinary optimization. Further topics include wall-modelled Large Eddy Simulation (WMLES), embedded LES,  Lattice-Bolzman methods, turbulence-resolving applications and comparisons between LES, hybrid RANS-LES and URANS methods. The book addresses academic researchers, graduate students, industrial engineers, as well as industrial R&D managers and consultants dealing with turbulence modelling, simulation and measurement, and with multidisciplinary applications of computational fluid dynamics.