This book focuses on information-geometric manifolds of structured data and models and related applied mathematics. It features new and fruitful interactions between several branches of science: Advanced Signal/Image/Video Processing, Complex Data Modeling and Analysis, Statistics on Manifolds, Topology/Machine/Deep Learning and Artificial Intelligence. The selection of applications makes the book a substantial information source, not only for academic scientist but it is also highly relevant for industry. The book project was initiated following discussions at the international conference GSI’2019 – Geometric Science of Information that was held at ENAC, Toulouse (France).