This book constitutes the refereed proceedings of the 15th International Conference on Reversible Computation, RC 2023, held in  Giessen, Germany, during July 18–19, 2023. The 11 full papers and 3 short papers included in this book were carefully reviewed and selected from 19 submissions. They were organized in topical sections as follows:? Foundations; Reversible Programming; Quantum Computing; and Quantum Circuits.