The convergence of nanotechnology and healthcare has paved the way for groundbreaking innovations. Smart nanomaterials, with their unique properties and capabilities, have emerged as key enablers for digital healthcare and biosensing applications. This proposed book aims to provide a thorough exploration of the latest developments, methodologies, and case studies in this dynamic and interdisciplinary domain. This book brings together a diverse group of experts, spanning the fields of nanotechnology, healthcare, and sustainability. The interdisciplinary approach ensures a holistic exploration of smart and sustainable nanomaterials, offering readers a comprehensive understanding of the subject from multiple perspectives. The book showcases the latest advancements in nanotechnology applied to digital healthcare and theranostic. Readers will gain insights into groundbreaking research, innovative applications, and real-world case studies, making it an invaluable resource for researchers, practitioners, and students seeking to stay at the forefront of this rapidly evolving field. A unique feature of this book is its dedicated focus on sustainable nanomaterials. As the world increasingly embraces eco-friendly practices, the book explores green synthesis methods, biodegradable nanomaterials, and sustainable applications in healthcare. This emphasis aligns with the growing demand for environmentally conscious solutions in the field of nanomedicine. Beyond theoretical discussions, the book provides practical guidance for implementing smart and sustainable nanomaterials in healthcare. It addresses challenges, ethical considerations, and regulatory aspects, offering readers actionable insights. Additionally, the exploration of future trends and perspectives ensures that the book remains relevant and forward-looking in a rapidly advancing technological landscape.