This book offers theoretical and empirical contributions on the approaches, policies, practices concerning the inclusion of migrants through social entrepreneurship. Grounded in a multi-disciplinary approach and with a special focus on the Adriatic-Ionian region, the book offers a debate on the antecedents, processes and outcomes of social entrepreneurship and migrants’ inclusion, describing some innovative initiatives and their potential transferability in other contexts. The Adriatic-Ionian macro-region represents an interesting yet overlooked area of research, characterized by evolving migration and inclusion policies, together with specific legislation and reforms for social entrepreneurship. The migration dynamics along the so-called Balkan Route confer to this macro-region strong political relevance in the field of security and migration management. Contributing to the targets of SDG 8, the book contextualizes the opportunities offered by social entrepreneurship as a form of decent work for migrants, and of potential growth driver for local and international territories.