Discrimination, stigmatization, xenophobia, heightened securitization – fear and blaming of "aliens within" – characterize the world infected by COVID-19. Such fears have a long cultural history, however, particularly in connecting pathology with race, poverty, and migration. This volume explores theory and narratives of disease, danger, and displacement through the lenses of cultural, literary, and film studies, historical representation, ethnics studies, sociology and cultural geography, classics, music, and linguistics. Investigations range from, for example, illness discourse in the ancient classics to images of perilous intruders in the Age of Trump, from the Haitian Revolution and subsequent zombie stereotypes to current, problematic refugee resettlement in the US South and Greek islands, from the urban underworld in nineteenth-century sensation novels to ethnic women "on the stroll" in coronavirus times. The collection is organized into three thematically intertwined parts: Stigmatizing the Racialized Underclass; Pathologizing the Other; Constructing and Countering Collapse. It examines changing or recurrent aporias in tropes of belonging and exclusion, as well as the birthing of new forms of identity, agency, and countercultural expression.