Frank Hirschinger gives an overview of the history of the annihilation of "life unworthy of life" in National Socialist Germany using the example of the city of Halle and the Altscherbitz State Sanatorium. The author provides evidence that medical professionals from Halle participated to a large extent in the ideological preparation and the later implementation of the "euthanasia". Peripheral areas of the extermination campaign that have so far received little attention from research, such as the extermination of anti-socials, criminals and prostitutes, are presented, as is the procedure against disabled children, Jews and foreign forced laborers placed in psychiatry. Numerous documents from German, Polish and Austrian archives are published for the first time as part of his investigation.