The World Health Organisation states that common, preventable risk factors underlie most non-communicable diseases. Most non-communicable diseases are the result of four particular behaviours: Tobacco use, physical inactivity, unhealthy diet and harmful use of alcohol. These behaviours lead to four key metabolic/physiological changes: Raised blood pressure, overweight/obesity, raised glucose, raised cholesterol. Our bodies are naturally adapted to filter out poisons, prevent them from doing harm and eliminate them from the body, but problems arise when large quantitites of toxins are consistently introduced over a length of time. In addition, environmental poisons increasingly impact on our bodies. As well as the chemicals used in growing and manufacturing food, smog and air pollution, synthetic food additives, artificial sweeteners and water impurities all add to the toxic load. This Guides presents the facts as helpful overview for intelligent consideration, and highlights how small changes in diet and lifestyle can increase well-being, vitality and general health.