The Spanish Caribbean and the Atlantic World in the Long Sixteenth Century breaks new ground in articulating the early Spanish Caribbean as a distinct and diverse group of colonies loosely united under Spanish rule for roughly a century prior to the establishment of other European colonies. In the sixteenth century no part of the Americas was more diverse; international; or as closely tied to Spain, the islands of the Atlantic, western Africa, and the Spanish American mainland than the Caribbean. The Caribbean experienced rapid growth during this period, displayed considerable ethnic and religious diversity, developed extensive networks of exchange both within and beyond the region, and played an important role in the broader Spanish colonization of the Americas. Contributors address topics such as the role of religious orders, the development of transatlantic and regional commercial systems, insular and regional political dynamics in relation to imperial objectives, the formation of colonial society, and the effects on Caribbean colonial society of the importation and incorporation of large numbers of indigenous captives and enslaved Africans.