This two-volume set constitutes the post-conference proceedings of the 6th EAI International Conference on Advanced Hybrid Information Processing, ADHIP 2022, held in Changsha, China, in September 29-30, 2022.

The 109 full  papers presented were selected from 276 submissions and focus on theory and application of hybrid information processing technology for smarter and more effective research and application. The theme of ADHIP 2022 was Hybrid Information Processing in Meta World. The papers are named in topical sections as follows: Information Extracting and Processing in Digital World; Education Based methods in Learning and Teaching; Various Systems for Digital World.