This 2-volume set CCIS 2014 and CCIS 2015 constitutes the post-conference proceedings of the First International Conference on Applied Intelligence, ICAI 2023, held in Nanning, China, December 8–12, 2023. The 64 full papers presented in this proceedings were carefully selected and reviewed from 228 submissions. The papers cover a wide range on theoretical aspects of biomedical data modeling and mining; computer vision; and deep learning. They were organized in topical sections as follows:Part I: Biomedical data modeling and mining; computer vision; deep learning; Part II: Intelligent control and automation; machine learning; natural language processing and computational linguistics.