This novel two-volume compilation presents scientific knowledge pertaining to the utilization of crude drugs, encompassing data on pharmacology and phytochemistry, ethnomedical applications, as well as the influence of adulterants and substitutes on human health for the prevention, treatment, and management of diseases. Crude Drugs in Unani Medicine is divided into two volumes, with the first volume exploring both the theoretical and practical aspects of potential medicinal plants and their bioactive compounds, either used individually or in combination within drug formulations, to combat a broad spectrum of chronic ailments, such as skin diseases, liver disorders, musculoskeletal conditions, reproductive system dysfunctions, immunological aberrations, and various other health issues. The second volume focuses on the pharmacology and phytochemistry of medicinal plants and animal-derived drugs, along with their pharmacovigilance. Crude Drugs of Unani Medicine: Volume 1: Application and Utility for Human Welfare delves into the understanding and application of Unani medicine (formerly referred to as Greco-Arab medicine) as a means of cure, rehabilitation, and promotion of human well-being. In the present day, medicinal plants or their bioactive compounds provide a multitude of possibilities within the Unani system of medicine. This serves as a fundamental framework, employing rational scientific theories and holistic concepts of health and healing to ensure safe diagnostic and therapeutic methods. The vast array of chemical and structural properties exhibited by medicinal plants has also been bolstered by the evolution of crude drugs, which can be utilized individually or in combination to promote human well-being. Crude Drugs of Unani Medicine: Volume 2: Phytochemistry and Pharmacology Aspects provides a comprehensive understanding of the pharmacology, phytochemistry, and pharmacovigilance of medicinal plants utilized in the traditional Unani system of medicine. The extensive range of possibilities presented by traditional medicine enables the utilization of potential therapeutic agents in the form of standardized extracts, in conjunction with other herbs or as isolated bioactive constituents. These agents possess diverse properties such as antiparasitic, antifungal, antiviral, antibacterial, antioxidant, and anticancer activities, which can be utilized as drug treatments for various systemic disorders. Moreover, these treatments have a positive impact on human health and are considered safe for consumption. Together, these two esteemed volumes offer a comprehensive resource on the use and administration of Unani drugs for diverse medical ailments. The valuable information provided here can enhance human immunity against a range of medical conditions while also avoiding undesirable side effects.