This novel two-volume compilation presents scientific knowledge pertaining to the utilization of crude drugs, encompassing data on pharmacology and phytochemistry, ethnomedical applications, as well as the influence of adulterants and substitutes on human health for the prevention, treatment, and management of diseases. Volume 1: Application and Utility for Human Welfare explores both the theoretical and practical aspects of potential medicinal plants and their bioactive compounds, either used individually or in combination within drug formulations, to combat a broad spectrum of chronic ailments, such as skin diseases, liver disorders, musculoskeletal conditions, reproductive system dysfunctions, immunological aberrations, and various other health issues. Volume 2: Phytochemistry and Pharmacology Aspects provides a comprehensive understanding of the pharmacology, phytochemistry, and pharmacovigilance of medicinal plants utilized in the traditional Unani system of medicine. It discusses the extensive range of possibilities presented by traditional medicine that enables the utilization of potential therapeutic agents in the form of standardized extracts, in conjunction with other herbs or as isolated bioactive constituents. These agents possess diverse properties such as antiparasitic, antifungal, antiviral, antibacterial, antioxidant, and anticancer activities, which can be utilized as drug treatments for various systemic disorders.