This book gathers the best papers presented at the third conference held by the Russian chapter of the Association for Information Systems (AIS), which took place in December 2021. The book shows the path to digital transformation of organizations and how possible obstacles can be overcome. With contributions from digital experts in both academia and IT and management, it presents practical frameworks and planning tools for new business models. It offers executives at the forefront of strategic initiatives a guide on how to implement key disruptive technologies in their organizations while following an established digital strategy. Overall, the book is relevant for scientists, digital technology users, companies and public institutions.