This book gathers the refereed proceedings of the 5th HFEM Biennial Conference on Human Factors and Ergonomics, organized by the Human Factors and Ergonomics Society Malaysia, held in Langkawi, Malaysia on August 13–18, 2023. Under the theme "Accelerating Human Factors and Ergonomics Toward an Inclusive and Sustainable Future", it highlights the latest theories and models, as well as cutting-edge technologies and applications on human factors and ergonomics. By combining findings from a range of disciplines including engineering, design, robotics, health care, management, computer science, human biology, and behavioral science, it offers an excellent source of innovative ideas to stimulate future discussions and developments aimed at applying knowledge and techniques to optimize system performance, while at the same time promoting the health, safety, and well-being of individuals. It includes papers from researchers and practitioners, scientists and physicians, institutional leaders, managers, and policy makers that contribute to constructing the human factors and ergonomics approach across a variety of methodologies, domains, and productive sectors.