The five-volume set LNCS 14355, 14356, 14357, 14358 and 14359 constitutes the refereed proceedings of the 12th International Conference on Image and Graphics, ICIG 2023, held in Nanjing, China, during September 22–24, 2023. The 166 papers presented in the proceedings set were carefully reviewed and selected from 409 submissions. They were organized in topical sections as follows: computer vision and pattern recognition; computer graphics and visualization; compression, transmission, retrieval; artificial intelligence; biological and medical image processing; color and multispectral processing; computational imaging; multi-view and stereoscopic processing; multimedia security; surveillance and remote sensing, and virtual reality. The ICIG 2023 is a biennial conference that focuses on innovative technologies of image, video and graphics processing and fostering innovation, entrepreneurship, and networking. It will feature world-classplenary speakers, exhibits, and high quality peer reviewed oral and poster presentations.