This book constitutes the proceedings of the 14th International Conference on Intelligent Tutoring Systems, IST 2018, held in Montreal, Canada, in June 2018.The 26 full papers and 22 short papers presented in this volume were carefully reviewed and selected from 120 submissions. In the back matter of the volume 20 poster papers and 6 doctoral consortium papers are included. They deal with the use of advanced computer technologies and interdisciplinary research for enabling, supporting and enhancing human learning.