This book constitutes the refereed proceedings of the 5th Iberoamerican Conference and 4th Indo-American Conference on Knowledge Graphs and Semantic Web, KGSWC 2023, held jointly in Zaragoza, Spain, during November 13–15, 2023. The 18 full and 2 short papers presented were carefully reviewed and selected from 50 submissions. They focus on the following topics: knowledge representation; natural language processing/text mining; and machine/deep learning research.