This book presents selected papers introducing readers to the key research topics and latest development trends in the theory and application of MMESE. The advanced integrated research topic man-machine-environment system engineering (MMESE) was first established in China by Professor Shengzhao Long in 1981, with direct support from one of the greatest modern Chinese scientists, Xuesen Qian. In a letter to Shengzhao Long from October 22nd, 1993, Xuesen Qian wrote: “You have created a very important modern science and technology in China!”MMESE primarily focuses on the relationship between man, machine and environment, studying the optimum combination of man-machine-environment systems, where “man” refers to people in the workplace (e.g., operators, decision-makers), “machine” is the general name for any object controlled by man (including tools, machinery, computers, systems and technologies), and “environment” describes the specific working conditions under which man and machine interact (e.g., temperature, noise, vibration and hazardous gases). The three goals of optimizing such systems are ensuring safety, efficiency and economy. Presenting interdisciplinary studies on the concepts and methods in physiology, psychology, system engineering, computer science, environmental science, management, education and other related disciplines, this book is a valuable resource for all researchers and professionals whose work involves MMESE subjects.