This book is a collection of high-quality research papers presented at International Conference on Smart Systems and Wireless Communication, SSWC 2025, organized by Department of Information Technology, JIS College of Engineering, Kalyani, West Bengal, India, during November 21–22, 2025. This book focuses on smart cities, smart farming, smart healthcare, wireless networks communication, internet of things, cyber physical systems, human computer interaction, big data and data analytics, high performance computing, requirements engineering, analysis and verification techniques, security systems, distributed systems, biometrics, bioinformatics, robotic process automation, and machine learning.